témavezető: Szabados László
helyszín (magyar oldal): MTA SzBK helyszín rövidítés: SzBK
A kutatási téma leírása:
Previously we have identified several regulatory genes, including zinc finger domain, heat shock and ERF/AP2 type transcription factors, which, upon overexpression, could increase salt tolerance or modify senstivity to abscisic acid in Arabidopsis. Analysis of those factors will be continued by molecular, genetic, biochemical and physiological methods. Stress tolerance characters of transgenic overexpressing Arabidopsis and other species such as poplar will be evaluated. New gene expression vectors with stress-induced promoters will be constructed and used for Agrobacterium-meiated transformation of Arabidopsis and poplar. Characters such as growth, survival will be analysed. Stress-related physiological features, including proline accumulation, photosynthesis, damage by reactive oxygen species will be tested. Regulatory pathways, controlling stress responses will be characterized by identification protein interacting partners, studying DNA or RNA binding characters of the identified factors.
The project is part of our long-term program to identify and characterize novel stress factors and evaluate their potential for biotechnological applications. The Ph.D. student will participate in the characterization of the already identified factors. The candidate should have experience in molecular, biochemical and genetic technologies, and be able to communicate, read and write in english.
Our recent publications in the area.
1. Rigó G, Tietz O, Ayaydin F, Zsigmond L, Kovács H, Páy A, Salchert K, Szabados L, Palme K, Koncz Cs, Cséplö Á (2013) Inactivation of plasma-membrane localized CDPK-related kinase 5 decelerates PIN2 exocytosis and root gravitropic response. Plant Cell 25:1592-1608
2. Ruibal C, Castro A, Carballo V, Szabados L, Vidal S (2013) Recovery from heat, salt and osmotic stress in Physcomitrella patens requires a functional small heat shock protein PpHsp16.4. BMC Plant Biol 13: 174
3. Perez-Salamo I, Papdi C, Rigo G, Zsigmond L, Vilela B, Lumbreras V, Nagy I, Horvath B, Domoki M, Darula Z, Medzihradszky K, Bogre L, Koncz C, Szabados L (2014) The Heat Shock Factor A4A Confers Salt Tolerance and Is Regulated by Oxidative Stress and the Mitogen-Activated Protein Kinases MPK3 and MPK6. Plant Physiol 165: 319-334
4. Joseph MP, Papdi C, Kozma-Bognar L, Nagy I, Lopez-Carbonell M, Koncz C, Szabados L (2014) The Arabidopsis Zinc Finger Protein 3 interferes with ABA and light signaling in seed germination and plant development. Plant Physiol (in press)
ajánlott nyelvtudás (magyar oldal): angol felvehető hallgatók száma: 1
Jelentkezési határidő: 2015-02-28
2024. IV. 17. ODT ülés Az ODT következő ülésére 2024. június 14-én, pénteken 10.00 órakor kerül sor a Semmelweis Egyetem Szenátusi termében (Bp. Üllői út 26. I. emelet).
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