témavezető: Nagy László
helyszín (magyar oldal): Debreceni Egyetem, Általános Orvostudományi Kar helyszín rövidítés: DEÁOK
A kutatási téma leírása:
Macrophages are a type of white blood cells that play a key role in the non-specific defence of the organism and also are involved in the initiation of the adaptive immunity. They are one of the first barriers of host defence against pathogens and also organize the healing of various injured tissues. In response to outer stimuli and tissue microenvironment they display either a proinflammatory phenotype (M1 subtype) or an alternative anti-inflammatory phenotype (M2 subtype). They are important cells for the healing of different tissues and therefore they contribute to homeostatic tissue repair and remodelling (Rigamonti et al., 2014).