ODT - THESIS TOPIC: Péter Kele: Design and development of ...


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Thesis topic proposal

Design and development of genetically modified virus-like nanoparticles for targeted drug-delivery

THESIS TOPIC PROPOSAL

Institute: Eötvös Loránd University, Budapest
chemistry
György Hevesy Doctoral School of Chemistry

Thesis supervisor: Péter Kele
Location of studies (in Hungarian): TTK Kémiai Intézet
Abbreviation of location of studies: Kém.

Description of the research topic:

This research topic involves the design and synthesis of virus capsids / envelopes bearing non-canonical amino acids (UAAs). These unnatural entities are to be implemented genetically (stop codon supression) and expressed in bacterial cells. These virus-proteins will be labeled fluorescently through the UAAs and allowed to self-organize and into virus-like nanoparticles. Such systems will be used to deliver certain drugs or dyes into specific cells.

Required language skills: good command of English
Further requirements:
preparative chemistry skills

Number of students who can be accepted: 1

Deadline for application: 2014-11-27

2024. IV. 17.
ODT ülés
Az ODT következő ülésére 2024. június 14-én, pénteken 10.00 órakor kerül sor a Semmelweis Egyetem Szenátusi termében (Bp. Üllői út 26. I. emelet).