Thesis supervisor: László Héja
Location of studies (in Hungarian): Research Centre for Natural Sciences, Hungary, 1117 Budapest, Magyar tudósok körútja 2. Abbreviation of location of studies: MTA
Description of the research topic:
The objective of the PhD student will be to identify novel drug targets for the treatment of pharmacoresistant epilepsy primarily by revealing and characterization of glia-neuron communication pathways. The potential drug targets will be investigated by:
1) simultaneous monitoring of neuronal and glial activity in wild-type and transgenic rats (expressing fluorescent Ca2+ sensitive reporter proteins) in vitro and in vivo using fluorescent two-photon imaging and electrophysiology;
2) pharmacological validation of the identified drug targets in in vitro epilepsy models;
3) development of novel methods for targeted investigation of the potential drug target mechanisms.
The tasks of the PhD student include the design and execution of the experiments, tracking of the literature and publication of the results.
Required language skills: English (fluent) Further requirements: MSc degree in the field of natural or life sciences
Proof of English proficiency
Due to the requirements of the scholarship the applicant should be below 30 years
Number of students who can be accepted: 2
Deadline for application: 2017-05-31
2024. IV. 17. ODT ülés Az ODT következő ülésére 2024. június 14-én, pénteken 10.00 órakor kerül sor a Semmelweis Egyetem Szenátusi termében (Bp. Üllői út 26. I. emelet).
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