Thesis topic proposal
László Nagy
Bioinformatics of ex vivo macrophages subtypes based on a muscle regeneration model


Institute: University of Debrecen
theoretical medicine
Doctoral School of Molecular Cellular and Immune Biology

Thesis supervisor: László Nagy
Location of studies: Debreceni Egyetem, Általános Orvostudományi Kar
Abbreviation of location of studies: DEÁOK

Description of the research topic:

Macrophages are a type of white blood cells that play a key role in the non-specific defence of the organism and also are involved in the initiation of the adaptive immunity. They are one of the first barriers of host defence against pathogens and also organize the healing of various injured tissues. In response to outer stimuli and tissue microenvironment they display either a proinflammatory phenotype (M1 subtype) or an alternative anti-inflammatory phenotype (M2 subtype). They are important cells for the healing of different tissues and therefore they contribute to homeostatic tissue repair and remodelling (Rigamonti et al., 2014).

Number of students who can be accepted: 1

Deadline for application: 2017-01-15

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