Éva Gráczer - ODT Personal data sheet

Publications

2016

Graczer E, Szimler T, Garamszegi A, Konarev PV, Labas A, Olah J, Pallo A, Svergun DI, Merli A, Zavodszky P, Weiss MS, Vas M: Dual Role of the Active Site Residues of Thermus thermophilus 3-Isopropylmalate Dehydrogenase: Chemical Catalysis and Domain Closure., BIOCHEMISTRY 55: (3) pp. 560-574.
type of document: Journal paper/Article
number of independent citations: 1
language: English
URL

2015

Gráczer Éva, Palló Anna, Oláh Julianna, Szimler Tamás, Konarev Petr V, Svergun Dmitri I, Merli Angelo, Závodszky Péter, Weiss Manfred S, Vas Mária: Glutamate 270 plays an essential role in K+-activation and domain closure of Thermus thermophilus isopropylmalate dehydrogenase, FEBS LETTERS 589: (2) pp. 240-245.
type of document: Journal paper/Article
number of independent citations: 1
language: English
URL

2014

Graczer E, Bacso A, Konya D, Kazi A, Soos T, Molnar L, Szimler T, Beinrohr L, Szilagyi A, Zavodszky P, Vas M: Drugs Against Mycobacterium Tuberculosis 3-Isopropylmalate Dehydrogenase Can be Developed using Homologous Enzymes as Surrogate Targets., PROTEIN AND PEPTIDE LETTERS 21: (12) pp. 1295-1307.
type of document: Journal paper/Article
number of independent citations: 1
language: English
URL

2014

Palló A, Oláh J, Gráczer E, Merli A, Závodszky P, Weiss MS, Vas M: Structural and energetic basis of isopropylmalate dehydrogenase enzyme catalysis, FEBS JOURNAL 281: (22) pp. 5063-5076.
type of document: Journal paper/Article
number of independent citations: 5
language: English
URL

2013

Varga A, Gráczer É, Chaloin L, Liliom K, Závodszky P, Lionne C, Vas M: Selectivity of kinases on the activation of tenofovir, an anti-HIV agent, EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES 48: (1-2) pp. 307-315.
type of document: Journal paper/Article
number of independent citations: 7
language: English
DOI

2011

Zerrad L, Merli A, Schroder GF, Varga A, Graczer E, Pernot P, Round A, Vas M, Bowler MW: A Spring-loaded Release Mechanism Regulates Domain Movement and Catalysis in Phosphoglycerate Kinase, JOURNAL OF BIOLOGICAL CHEMISTRY 286: (16) pp. 14040-14048.
type of document: Journal paper/Article
number of independent citations: 19
language: English
DOI

2010

Vas M, Varga A, Gráczer E: Insight into the mechanism of domain movements and their role in enzyme function: example of 3-phosphoglycerate kinase., CURRENT PROTEIN AND PEPTIDE SCIENCE 11: (2) pp. 118-147.
type of document: Journal paper/Review paper
number of independent citations: 12
language: English
DOI

2007

Graczer E, Varga A, Hajdu I, Melnik B, Szilagyi A, Semisotnov G, Zavodszky P, Vas M: Rates of unfolding, rather than refolding, determine thermal stabilities of thermophilic, mesophilic, and psychrotrophic 3-isopropylmalate dehydrogenases, BIOCHEMISTRY 46: (41) pp. 11536-11549.
type of document: Journal paper/Article
number of independent citations: 7
language: English
DOI

2006

Varga A, Flachner B, Konarev P, Gráczer E, Szabó J, Svergun D, Závodszky P, Vas M: Substrate-induced double sided H-bond network as a means of domain closure in 3-phosphoglycerate kinase, FEBS LETTERS 580: pp. 2698-2706.
type of document: Journal paper/Article
number of independent citations: 10
language: English
DOI

2005

Varga A, Flachner B, Graczer E, Osvath S, Szilagyi AN, Vas M: Correlation between conformational stability of the ternary enzyme-substrate complex and domain closure of 3-phosphoglycerate kinase, FEBS JOURNAL 272: (8) pp. 1867-1885.
type of document: Journal paper/Article
number of independent citations: 15
language: English
DOI

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