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personal data approved: 2016. II. 02.
Personal data
name Mária Kazinczyné Vas
year of birth 1941
name of institution
doctoral school
BME George A. Olah Doctoral School of Chemistry and Chemical Technology (Academic staff member)
ELTE Doctoral School of Chemistry (Academic staff member)
ELTE Doctoral School of Biology (Academic staff member)
the share of work in the different doctoral schools. BME George A. Olah Doctoral School of Chemistry and Chemical Technology 25%
ELTE Doctoral School of Chemistry 25%
ELTE Doctoral School of Biology 50%
Contact details
E-mail address vas.mariattk.mta.hu
phone number +36 1 279-3152
own web page
Academic title
scientific degree, title CSc
year degree was obtained 1976
discipline to which degree belongs biology
institution granting the degree HAS
scientific degree, title DSc
year degree was obtained 1996
discipline to which degree belongs biology
institution granting the degree HAS
Employment
2014 - MTA TTK Enzimológiai Intézet (research institute, not university)
other (not specified) (önkéntes tudományos tanácsadó)
Thesis topic supervisor
number of doctoral students supervised until now 4.5
number of students who fulfilled course requirements 4.5
students who obtained their degrees:
Éva Laura Gráczer PhD 2010  DSB-ELTE
Judit Perbiróné Szabó PhD 2009  DSB-ELTE
(50%) Andrea Matkovicsné Varga PhD 2007  
(50%) Beáta Flachner PhD 2004  GAODSCC
(50%) Zoltán Kovári PhD 2004  
Andrea Szilágyi PhD 1999  

  Thesis topic proposals
Research
research area The role of modular organisation of proteins in formation of the three-dimensional structure and in fullfilment of the catalytic properties are investigated.
research field in which current research is conducted biology
Publications
2015

Gráczer Éva, Palló Anna, Oláh Julianna, Szimler Tamás, Konarev Petr V, Svergun Dmitri I, Merli Angelo, Závodszky Péter, Weiss Manfred S, Vas Mária: Glutamate 270 plays an essential role in K+-activation and domain closure of Thermus thermophilus isopropylmalate dehydrogenase, FEBS LETTERS 589: (2) pp. 240-245.
type of document: Journal paper/Article
language: English
DOI 
2014

Palló A, Oláh J, Gráczer E, Merli A, Závodszky P, Weiss MS, Vas M: Structural and energetic basis of isopropylmalate dehydrogenase enzyme catalysis, FEBS JOURNAL 281: (22) pp. 5063-5076.
type of document: Journal paper/Article
language: English
URL 
2013

Graczer Eva, Lionne Corinne, Zavodszky Peter, Chaloin Laurent, Vas Maria: Transient kinetic studies reveal isomerization steps along the kinetic pathway of Thermusthermophilus 3-isopropylmalate dehydrogenase, FEBS JOURNAL 280: (8) pp. 1764-1772.
type of document: Journal paper/Article
language: English
URL 
2011

Zerrad L, Merli A, Schroder GF, Varga A, Graczer E, Pernot P, Round A, Vas M, Bowler MW: A Spring-loaded Release Mechanism Regulates Domain Movement and Catalysis in Phosphoglycerate Kinase, JOURNAL OF BIOLOGICAL CHEMISTRY 286: (16) pp. 14040-14048.
type of document: Journal paper/Article
number of independent citations: 16
language: English
DOI 
2011

Graczer E, Merli A, Singh RK, Karuppasamy M, Zavodszky P, Weiss MS, Vas M: Atomic level description of the domain closure in a dimeric enzyme: Thermus thermophilus 3-isopropylmalate dehydrogenase, MOLECULAR BIOSYSTEMS 7: (5) pp. 1646-1659.
type of document: Journal paper/Article
number of independent citations: 2
language: English
DOI 
2010

Vas M, Varga A, Gráczer E: Insight into the mechanism of domain movements and their role in enzyme function: example of 3-phosphoglycerate kinase., CURRENT PROTEIN AND PEPTIDE SCIENCE 11: (2) pp. 118-147.
type of document: Journal paper/Article
number of independent citations: 10
language: English
2010

Cliff MJ, Bowler MW, Varga A, Marston JP, Szabo J, Hounslow AM, Baxter NJ, Blackburn GM, Vas M, Waltho JP: Transition state analogue structures of human phosphoglycerate kinase establish the importance of charge balance in catalysis., JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 132: (18) pp. 6507-6516.
type of document: Journal paper/Article
number of independent citations: 34
language: English
DOI 
2008

Moniot S, Bruno S, Vonrhein C, Didierjean C, Boschi-Muller S, Vas M, Bricogne G, Branlant G, Mozzarelly A, Corbier C: Trapping of the Thioacylglyceraldehyde - 3- phosphate Dehydrogenase Intermediate from Bacillus stearothermophilus: DIRECT EVIDENCE FOR A FLIP-FLOP MECHANISM, JOURNAL OF BIOLOGICAL CHEMISTRY 283: (31) pp. 21693-21702.
type of document: Journal paper/Article
number of independent citations: 10
language: English
2008

Gondeau C, Chaloin L, Lallemand P, Roy B, Périgaud C, Barman T, Varga A, Vas M, Lionne C, Arold ST: Molecular basis for the lack of enantioselectivity of human 3-phosphoglycerate kinase, NUCLEIC ACIDS RESEARCH 36: (11) pp. 3620-3629.
type of document: Journal paper/Article
number of independent citations: 9
language: English
1992

HARLOS K, VAS M, BLAKE CCF: Crystal structure of the binary complex of pig muscle phosphoglycerate kinase and its substrate 3-phospho-Dglycerate, PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS 12: (2) pp. 133-144.
type of document: Journal paper/Article
number of independent citations: 87
language: English
DOI 
Number of independent citations to these publications:168 
Scientometric data
list of publications and citations
number of scientific publications that meet accreditation criteria:
86
number of scientific publications:
94
monographs and professional books:
0
monographs/books in which chapters/sections were contributed:
2 
scientific publications published abroad that meet the accreditation criteria:
70
publications not in Hungarian, published in Hungary, meeting the accreditation criteria:
11
number of independent citations to scientific publications and creative works:
672

 
All rights reserved © 2007, Hungarian Doctoral Council. Doctoral Council registration number at commissioner for data protection: 02003/0001. Program version: 1.2318 ( 2016. XI. 26. )