Login
 Forum
 
 
Personal data sheet
 Print preview
personal data approved: 2016. XI. 17.
Personal data
Gabriella Spengler
name Gabriella Spengler
year of birth 1978
name of institution
doctoral school
SzTE Doctoral School of Interdisciplinary Medicine (Supervisor)
Contact details
E-mail address spengler.gabriellamed.u-szeged.hu
phone number +36 62 545-115
own web page
Academic title
scientific degree, title Ph.D.
year degree was obtained 2006
discipline to which degree belongs theoretical medicine
institution granting the degree University of Szeged
Employment
2013 - University of Szeged
other (not specified) (tudományos munkatárs)
Thesis topic supervisor
number of doctoral students supervised until now
number of students who fulfilled course requirements
students who obtained their degrees:
present PhD students:
Annamária Kincses (PhD) (2018/08)  IDS-SzTE
Márió Gajdács (PhD) (2018/08)  IDS-SzTE
  Thesis topic proposals
Research
research area Multidrug resistance in bacteria and tumour cells, reversal of multidrug resistance,investigation of multidrug efflux pumps, efflux pump inhibitors (EPI), bacterial stress response, quorum sensing
research field in which current research is conducted theoretical medicine
Publications
2016

Kovács Dávid, Szőke Krisztina, Igaz Nóra, Spengler Gabriella, Molnár József, Tóth Tímea, Madarász Dániel, Rázga Zsolt, Kónya Zoltán, Boros Imre M, Kiricsi Mónika: Silver nanoparticles modulate ABC transporter activity and enhance chemotherapy in multidrug resistant cancer, NANOMEDICINE: NANOTECHNOLOGY BIOLOGY AND MEDICINE 2016: p. 1.
type of document: Journal paper/Article
language: English
DOI 
2016

Domínguez-Álvarez E, Gajdács M, Spengler G, Palop JA, Marć MA, Kieć-Kononowicz K, Amaral L, Molnár J, Jacob C, Handzlik J, Sanmartín C: Identification of selenocompounds with promising properties to reverse cancer multidrug resistance, BIOORGANIC & MEDICINAL CHEMISTRY LETTERS 26: (12) pp. 2821-2824.
type of document: Journal paper/Article
language: English
URL 
2016

Zeslawska E, Kincses A, Spengler G, Nitek W, Wyrzuc K, Kiec-Kononowicz K, Handzlik J: The 5-aromatic hydantoin-3-acetate derivatives as inhibitors of the tumour multidrug resistance efflux pump P-glycoprotein (ABCB1): Synthesis, crystallographic and biological studies., BIOORGANIC & MEDICINAL CHEMISTRY 24: (12) pp. 2815-2822.
type of document: Journal paper/Article
language: English
DOI 
2016

Aliona Dobrova, Sonja Platzer, Felix Bacher, Miljan N M Milunovic, Anatolie Dobrov, Gabriella Spengler, Éva A Enyedy, Ghenadie Novitchi, Vladimir B Arion: Structure-antiproliferative activity studies on L-proline- and homoproline-4-N-pyrrolidine-3-thiosemicarbazone hybrids and their nickel(II), palladium(II) and copper(II) complexes, DALTON TRANSACTIONS 45: pp. 13427-13439.
type of document: Journal paper/Article
language: English
URL 
2016

Reis MA, Ahmed OB, Spengler G, Molnár J, Lage H, Ferreira M-JU: Jatrophane diterpenes and cancer multidrug resistance - ABCB1 efflux modulation and selective cell death induction, PHYTOMEDICINE 23: (9) pp. 968-978.
type of document: Journal paper/Article
language: English
DOI 
2016

Kincses A, Szabo AM, Saijo R, Watanabe G, Kawase M, Molnar J, Spengler G: Fluorinated Beta-diketo Phosphorus Ylides Are Novel Efflux Pump Inhibitors in Bacteria., IN VIVO 30: (6) pp. 813-817.
type of document: Journal paper/Article
language: English
2015

Takacs D, Csonka A, Horvath A, Windt T, Gajdacs M, Riedl Z, Hajos G, Amaral L, Molnar J, Spengler G: Reversal of ABCB1-related Multidrug Resistance of Colonic Adenocarcinoma Cells by Phenothiazines., ANTICANCER RESEARCH 35: (6) pp. 3245-3251.
type of document: Journal paper/Article
language: English
2015

Spengler G, Ocsovszki I, Tonki AS, Saijo R, Watanabe G, Kawase M, Molnar J: Fluorinated beta-Diketo Phosphorus Ylides Are Novel Inhibitors of the ABCB1 Efflux Pump of Cancer Cells., ANTICANCER RESEARCH 35: (11) pp. 5915-5919.
type of document: Journal paper/Article
language: English
URL 
2014

Cátia Vieira Noélia Duarte, Mariana A Reis, Gabriella Spengler, Ana Margarida Madureira, Joseph Molnar, Maria-José U Ferreira: Improving the MDR reversal activity of 6,17-epoxylathyrane diterpenes, BIOORGANIC & MEDICINAL CHEMISTRY 22: (22) pp. 6392-6400.
type of document: Journal paper/Article
number of independent citations: 1
language: English
DOI 
2012

Spengler G, Rodrigues L, Martins A, Martins M, McCusker M, Cerca P, Machado L, Costa SS, Ntokou E, Couto I, Viveiros M, Fanning S, Molnar J, Amaral L: Genetic response of Salmonella enterica serotype Enteritidis to thioridazine rendering the organism resistant to the agent, INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS 39: (1) pp. 16-21.
type of document: Journal paper/Article
number of independent citations: 7
language: English
DOI 
Number of independent citations to these publications:
Scientometric data
list of publications and citations
number of scientific publications that meet accreditation criteria:
60
number of scientific publications:
84
monographs and professional books:
0
monographs/books in which chapters/sections were contributed:
4 
scientific publications published abroad that meet the accreditation criteria:
56
publications not in Hungarian, published in Hungary, meeting the accreditation criteria:
3
number of independent citations to scientific publications and creative works:
411
further relevant information regarding accreditation (in Hungarian)
•2003-4: Magyar-Német TéT Bilat •2004-5: Magyar-Török TéT Bilat •2004-5: DAAD Magyar-Német Kutatócsere •2005-6: Magyar-Kínai TéT Bilat •2012-13: Magyar-Japán TéT Bilat 2010-13: Új kemoterápiás stratégiák a MDR tuberkulózis ellen; támogató: FCT, Portugália 2010-13: Helper vegyületek hatásmechanizmusa MDR baktériumok ellen; támogató: FCT, Portugália 2013-15: P-gp modulátorok optimalizációja és hatásuk rákos sejtek efflux mechanizmusára; támogató: FCT, PT (to be translated)

 
All rights reserved © 2007, Hungarian Doctoral Council. Doctoral Council registration number at commissioner for data protection: 02003/0001. Program version: 1.2318 ( 2016. XI. 26. )