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personal data approved: 2015. IX. 22.
Personal data
László Gráf
name László Gráf
year of birth 1942
name of institution
doctoral school
ELTE Doctoral School of Biology (Core member emeritus)
(discipline) Doctoral Council
ELTE Doctoral School of Physics
(discipline) Doctoral Council
ELTE Doctoral School of Earth Sciences
(discipline) Doctoral Council
ELTE Doctoral School of Chemistry
(discipline) Doctoral Council
ELTE Doctoral School of Environmental Sciences
(discipline) Doctoral Council
ELTE Doctoral School of Mathematics
(discipline) Doctoral Council
the share of work in the different doctoral schools. ELTE Doctoral School of Biology 94%
ELTE DSP2-ELTE (discipline) Doctoral Council 1%
ELTE DSB-ELTE (discipline) Doctoral Council 1%
ELTE DSES1-ELTE (discipline) Doctoral Council 1%
ELTE DSC-ELTE (discipline) Doctoral Council 1%
ELTE DSES2-ELTE (discipline) Doctoral Council 1%
ELTE DSM (discipline) Doctoral Council 1%
accreditation statement submitted to: Eötvös Loránd University, Budapest
Contact details
E-mail address grafelte.hu
phone number +36 1 372-2500/8781
own web page
Academic title
scientific degree, title CSc
year degree was obtained 1972
discipline to which degree belongs biology
institution granting the degree HAS
scientific degree, title Member of Hung. Acad. of Sci.
year degree was obtained 2001
discipline to which degree belongs biology
institution granting the degree HAS
Employment
2012 - Eötvös Loránd University, Budapest
professor emeritus
Thesis topic supervisor
number of doctoral students supervised until now 15.5
number of students who fulfilled course requirements 13.5
students who obtained their degrees:
Balázs Jelinek PhD 2008  DSB-ELTE
Borbála Szenthe PhD 2008  DSB-ELTE
Erika Rozália Siklódi PhD 2008  DSB-ELTE
Linda Gombos PhD 2008  DSB-ELTE
Judit Marokházi PhD 2005  DSB-ELTE
Erika Szabó PhD 2004  DSB-ELTE
(50%) Péter Hudáky PhD 2004  DSB-ELTE
Amir Sumaira PhD 2002  DSB-ELTE
Árpád Bódi PhD 2002  DSB-ELTE
Attila Reményi PhD 2002  DSB-ELTE
József Antal PhD 2002  DSB-ELTE
Zulfiqar Malik PhD 2002  DSB-ELTE
Gábor Pál PhD 1997  DSB-ELTE
Gyula Kaslik PhD 1997  DSB-ELTE

students with degree granting in process:
Kornél Takáts PhD (2016/12)  DSB-ELTE
  Thesis topic proposals
Research
research area Biochemistry, protein engineering. Molecular dynamics in serine protease action and their inhibition by canonical inhibitors. Protein stability studies in trypsin-trypsin inhibitor complexes.
research field in which current research is conducted biology
Publications
2013

Molnár Tamás, Vörös Judit, Szeder Bálint, Takáts Kornél, Kardos József, Katona Gergely, Gráf László: Comparison of complexes formed by a crustacean and a vertebrate trypsin with bovine pancreatic trypsin inhibitor – the key to achieving extreme stability?, FEBS JOURNAL 280: p. n/a.
type of document: Journal paper/Article
impact factor: 4.250*
language: English
DOI 
2011

Wahlgren WY, Pal G, Kardos J, Porrogi P, Szenthe B, Patthy A, Graf L, Katona G: The Catalytic Aspartate Is Protonated in the Michaelis Complex Formed between Trypsin and an in Vitro Evolved Substrate-like Inhibitor: A REFINED MECHANISM OF SERINE PROTEASE ACTION., JOURNAL OF BIOLOGICAL CHEMISTRY 286: (5) pp. 3587-3596.
type of document: Journal paper/Article
impact factor: 4.773
number of independent citations: 7
language: English
DOI 
2011

Rauscher AA, Simon Z, Szollosi GJ, Graf L, Derenyi I, Malnasi-Csizmadia A: Temperature dependence of internal friction in enzyme reactions, FASEB JOURNAL 25: (8) pp. 2804-2813.
type of document: Journal paper/Article
impact factor: 5.712
number of independent citations: 1
language: English
DOI 
2011

Voros K, Graf L Jr, Prohaszka Z, Graf L, Szenthe P, Kaszas E, Borocz Z, Cseh K, Kalabay L: Serum fetuin-A in metabolic and inflammatory pathways in patients with myocardial infarction., EUROPEAN JOURNAL OF CLINICAL INVESTIGATION 41: (7) pp. 703-709.
type of document: Journal paper/Article
impact factor: 3.018
number of independent citations: 7
language: English
DOI 
2010

Tarnok K, Szilagyi L, Berki T, Nemeth P, Graf L, Schlett K: Anoxia leads to a rapid translocation of human trypsinogen 4 to the plasma membrane of cultured astrocytes., JOURNAL OF NEUROCHEMISTRY 115: (2) pp. 314-324.
type of document: Journal paper/Article
impact factor: 4.337
language: English
DOI 
2008

Gombos L, Kardos J, Patthy A, Medveczky P, Szilagyi L, Malnasi-Csizmadia A, Graf L: Probing conformational plasticity of the activation domain of trypsin: The role of glycine hinges, BIOCHEMISTRY 47: (6) pp. 1675-1684.
type of document: Journal paper/Article
impact factor: 3.379
number of independent citations: 8
language: English
DOI 
2005

Fodor K, Harmat V, Hetenyi C, Kardos J, Antal J, Perczel A, Patthy A, Katona G, Graf L: Extended intermolecular interactions in a serine protease-canonical inhibitor complex account for strong and highly specific inhibition, JOURNAL OF MOLECULAR BIOLOGY 350: (1) pp. 156-169.
type of document: Journal paper/Article
impact factor: 5.229
number of independent citations: 20
language: English
DOI 
1988

GRAF L, JANCSO A, SZILAGYI L, HEGYI G, PINTER K, NARAYSZABO G, HEPP J, MEDZIHRADSZKY K, RUTTER WJ: ELECTROSTATIC COMPLEMENTARITY WITHIN THE SUBSTRATE-BINDING POCKET OF TRYPSIN, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 85: (14) pp. 4961-4965.
type of document: Journal paper/Article
impact factor: 10.032
number of independent citations: 107
language: English
DOI 
1985

EBINA Y, ELLIS L, JARNAGIN K, EDERY M, GRAF L, CLAUSER E, OU JH, MASIARZ F, KAN YW, GOLDFINE ID, ROTH RA, RUTTER WJ: THE HUMAN INSULIN-RECEPTOR CDNA - THE STRUCTURAL BASIS FOR HORMONE-ACTIVATED TRANSMEMBRANE SIGNALING, CELL 40: (4) pp. 747-758.
type of document: Journal paper/Article
impact factor: 18.871
number of independent citations: 1122
language: English
1976

GRAF L, SZEKELY JI, RONAI AZ, DUNAIKOVACS Z, BAJUSZ S: COMPARATIVE-STUDY ON ANALGESIC EFFECT OF MET5-ENKEPHALIN AND RELATED LIPOTROPIN FRAGMENTS, NATURE 263: (5574) pp. 240-241.
type of document: Journal paper/Article
impact factor: 5.582
number of independent citations: 114
language: English
Number of independent citations to these publications:1386 
Scientometric data
list of publications and citations
number of scientific publications that meet accreditation criteria:
163
number of scientific publications:
194
monographs and professional books:
0
monographs/books in which chapters/sections were contributed:
35 
scientific publications published abroad that meet the accreditation criteria:
143
publications not in Hungarian, published in Hungary, meeting the accreditation criteria:
16
number of independent citations to scientific publications and creative works:
3980

 
All rights reserved © 2007, Hungarian Doctoral Council. Doctoral Council registration number at commissioner for data protection: 02003/0001. Program version: 1.2318 ( 2016. XI. 26. )