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personal data approved: 2023. VII. 24.
Personal data
Lajos Mátés
name Lajos Mátés
name of institution
doctoral school
SzTE Doctoral School of Multidisciplinary Medical Scienses (Supervisor)
SzTE Doctoral School of Biology (Academic staff member)
the share of work in the different doctoral schools. SzTE Doctoral School of Multidisciplinary Medical Scienses 50%
SzTE Doctoral School of Biology 50%
Contact details
E-mail address matesbrc.hu
phone number +36 62 599-600
Academic title
scientific degree, title Ph.D.
year degree was obtained 2004
discipline to which degree belongs biology
institution granting the degree SZTE AOK (to be translated)
Employment
2010 - Magyar Tudományos Akadémia Szegedi Biológiai Kutatóközpont (research institute, not university)
other (not specified) (Tudomanyos munkatars)
Thesis topic supervisor
number of doctoral students supervised until now 5
number of students who fulfilled course requirements 1
students who obtained their degrees:
(50%) Bashir Sanam PhD 2014  
(50%) Devaraj Anantharam PhD 2014  

students with degree granting in process:
Khaldoon Sadiq Ahmed Abdullah PhD (2024/08)  DSMMS
completed course requirement:
Andrea Bakné Drubi (PhD) 2020/08  USz-DSB
Dávid Zsolt Pusztai (PhD) 2014/08  USz-DSB
Gergely Imre (PhD) 2017/08  USz-DSB
present PhD students:
May Raya (PhD) (2026/08)  DSMMS
Réka Karkas (PhD) (2024/08)  DSMMS
  Thesis topic proposals
Research
research area cancer research, genome manipulations, gene therapy, mobile genetic elements
research field in which current research is conducted biology
Publications
2023

Imre Gergely, Takács Bertalan, Czipa Erik, Drubi Andrea Bakné, Jaksa Gábor, Latinovics Dóra, Nagy Andrea, Karkas Réka, Hudoba Liza, Vásárhelyi Bálint Márk, Pankotai-Bodó Gabriella, Blastyák András, Hegedűs Zoltán, Germán Péter, Bálint Balázs, Ahmed Abdullah Khaldoon Sadiq, Kopasz Anna Georgina, Kovács Anita, Nagy László G., Sükösd Farkas, Pintér Lajos, Rülicke Thomas, Barta Endre, Nagy István, Haracska Lajos, Mátés Lajos: Prolonged activity of the transposase helper may raise safety concerns during DNA transposon-based gene therapy, MOLECULAR THERAPY-METHODS AND CLINICAL DEVELOPMENT 29: pp. 145-159.
type of document: Journal paper/Article
language: English
URL 
2022

Kopasz Anna Georgina, Pusztai Dávid Zsolt, Karkas Réka, Hudoba Liza, Abdullah Khaldoon Sadiq Ahmed, Imre Gergely, Pankotai-Bodó Gabriella, Migh Ede, Nagy Andrea, Kriston András, Germán Péter, Drubi Andrea Bakné, Molnár Anna, Fekete Ildikó, Dani Virág Éva, Ocsovszki Imre, Puskás László Géza, Horváth Péter, Sükösd Farkas, Mátés Lajos: A versatile transposon-based technology to generate loss- and gain-of-function phenotypes in the mouse liver, BMC BIOLOGY 20: (1) 74
type of document: Journal paper/Article
language: English
URL 
2016

Voigt F, Wiedemann L, Zuliani C, Querques I, Sebe A, Mates L, Izsvak Z, Ivics Z, Barabas O: Sleeping Beauty transposase structure allows rational design of hyperactive variants for genetic engineering, NATURE COMMUNICATIONS 7: 11126
type of document: Journal paper/Article
number of independent citations: 23
language: English
URL 
2014

Ivics Z, Mátés L, Yau TY, Landa V, Zidek V, Bashir S, Hoffmann OI, Hiripi L, Garrels W, Kues WA, Bösze Z, Geurts A, Pravenec M, Rülicke T, Izsvák Z: Germline transgenesis in rodents by pronuclear microinjection of Sleeping Beauty transposons, NATURE PROTOCOLS 9: (4) pp. 773-793.
type of document: Journal paper/Article
number of independent citations: 21
language: English
URL 
2013

Katter K, Geurts AM, Hoffmann Orsolya, Mates L, Landa V, Hiripi L, Moreno C, Lazar J, Bashir S, Zidek V, Popova E, Jerchow B, Becker K, Devaraj A, Walter I, Grzybowksi M, Corbett M, Filho AR, Hodges MR, Bader M, Ivics Z, Jacob HJ, Pravenec M, Bosze Z, Rulicke T, Izsvak Z: Transposon-mediated transgenesis, transgenic rescue, and tissue-specific gene expression in rodents and rabbits., FASEB JOURNAL 27: (3) pp. 930-941.
type of document: Journal paper/Article
number of independent citations: 42
language: English
URL 
2013

Xie Y, Mates L, Ivics Z, Izsvak Z, Martin SL, An WF: Cell division promotes efficient retrotransposition in a stable L1 reporter cell line, MOBILE DNA 4: 10
type of document: Journal paper/Article
number of independent citations: 37
language: English
URL 
2010

Grabundzija I, Irgang M, Mates L, Belay E, Matrai J, Gogol-Doring A, Kawakami K, Chen W, Ruiz P, Chuah MKL, VandenDriessche T, Izsvak Z, Ivics Z: Comparative Analysis of Transposable Element Vector Systems in Human Cells, MOLECULAR THERAPY 18: (6) pp. 1200-1209.
type of document: Journal paper/Article
number of independent citations: 133
language: English
URL 
2009

Xue XK, Huang X, Nodland SE, Mates L, Ma LA, Izsvak Z, Ivics Z, LeBien TW, McIvor RS, Wagner JE, Zhou XZ: Stable gene transfer and expression in cord blood-derived CD34(+)hematopoietic stem and progenitor cells by a hyperactive SleepingBeauty transposon system, BLOOD 114: (7) pp. 1319-1330.
type of document: Journal paper/Article
number of independent citations: 67
language: English
URL 
2009

Ivics Z, Li MA, Mates L, Boeke JD, Nagy A, Bradley A, Izsvak Z: Transposon-mediated genome manipulation in vertebrates, NATURE METHODS 6: (6) pp. 415-422.
type of document: Journal paper/Review paper
number of independent citations: 181
language: English
URL 
2009

Mates L, Chuah MKL, Belay E, Jerchow B, Manoj N, Acosta-Sanchez A, Grzela DP, Schmitt A, Becker K, Matrai J, Ma L, Samara-Kuko E, Gysemans C, Pryputniewicz D, Miskey C, Fletcher B, VandenDriessche T, Ivics Z, Izsvak Z: Molecular evolution of a novel hyperactive Sleeping Beauty transposase enables robust stable gene transfer in vertebrates, NATURE GENETICS 41: (6) pp. 753-761.
type of document: Journal paper/Article
number of independent citations: 482
language: English
URL 
Number of independent citations to these publications:986 
Scientometric data
Saját közlemény- és idézőlista list of publications and citations
number of scientific publications that meet accreditation criteria:
49
number of scientific publications:
49
monographs and professional books:
0
monographs/books in which chapters/sections were contributed:
1 
number of independent citations to scientific publications and creative works:
1625

 
All rights reserved © 2007, Hungarian Doctoral Council. Doctoral Council registration number at commissioner for data protection: 02003/0001. Program version: 2.2358 ( 2017. X. 31. )