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personal data approved: 2023. VII. 10.
Personal data
name Miklós Sahin-Tóth
name of institution
doctoral school
SE Doctoral School of Molecular Medicine (Academic staff member)
SzTE Doctoral School of Interdisciplinary Medicine (Announcer of research topic)
SzTE Theoretical Medicine Doctoral School (Academic staff member)
SE Doctoral School of University Semmelweis (Academic staff member)
the share of work in the different doctoral schools. SzTE Doctoral School of Interdisciplinary Medicine 20%
SzTE Theoretical Medicine Doctoral School 60%
SE Doctoral School of University Semmelweis 20%
Academic title
scientific degree, title Ph.D.
year degree was obtained 1994
discipline to which degree belongs theoretical medicine
institution granting the degree Semmelweis Orvostudományi Egyetem (to be translated)
scientific degree, title CSc
year degree was obtained 1994
discipline to which degree belongs theoretical medicine
institution granting the degree HAS
Employment
2019 - University of California Los Angeles
research professor
Thesis topic supervisor
number of doctoral students supervised until now 5
number of students who fulfilled course requirements 5
students who obtained their degrees:
(50%) Zsófia Pesei PhD 2023  TMDS
(50%) Anna Zsófia Tóth PhD 2018  TMDS
(50%) Anita Balázs PhD 2015  TMDS
(50%) Balázs Németh PhD 2014  IDS-SzTE
(50%) Andrea Geisz PhD 2013  TMDS
(50%) Melinda Bence PhD 2012  DSMM-SE
Orsolya Király PhD 2008  DSMM-SE
Richárd Szmola PhD 2008  DSMM-SE

  Thesis topic proposals
Research
research area Pathobiochemistry of pancreatitis. Genetic risk factors in chronic pancreatitis. The role of digestive enzymes in the development of pancreatitis.
research field in which current research is conducted theoretical medicine
biology
Publications
2022

Demcsak Alexandra, Sahin-Toth Miklos: Rate of Autoactivation Determines Pancreatitis Phenotype in Trypsinogen Mutant Mice, GASTROENTEROLOGY 163: (3) pp. 761-763.
type of document:
language: English
URL 
2022

Jancso Zsanett, Demcsak Alexandra, Sahin-Toth Miklos: Modelling chronic pancreatitis as a complex genetic disease in mice, GUT
type of document:
language: English
URL 
2020

Hegyi Eszter, Tóth Anna Zsófia, Vincze Áron, Szentesi Andrea, Hegyi Péter, Sahin-Tóth Miklós: Alcohol-dependent effect of PRSS1-PRSS2 haplotype in chronic pancreatitis, GUT 69: (9) pp. 1713-1715.
type of document:
number of independent citations: 7
language: English
URL 
2020

Jancso Zsanett, Sahin-Toth Miklos: Mutation That Promotes Activation of Trypsinogen Increases Severity of Secretagogue-Induced Pancreatitis in Mice, GASTROENTEROLOGY 158: (4) pp. 1083-1094.
type of document: Journal paper/Article
number of independent citations: 11
language: English
URL 
2019

Mayerle Julia, Sendler Matthias, Hegyi Eszter, Beyer Georg, Lerch Markus M, Sahin-Tóth Miklós: Genetics, Cell Biology, and Pathophysiology of Pancreatitis, GASTROENTEROLOGY 156: (7) pp. 1951-1968.
type of document: Journal paper/Article
number of independent citations: 89
language: English
URL 
2019

Geisz Andrea, Jancso Zsanett, Nemeth Balazs Csaba, Hegyi Eszter, Sahin-Toth Miklos: Natural single-nucleotide deletion in chymotrypsinogen C gene increases severity of secretagogue-induced pancreatitis in C57BL/6 mice, JCI INSIGHT 4: (14) e129717
type of document: Journal paper/Article
number of independent citations: 7
language: English
URL 
2019

Hegyi E, Sahin-Tóth M: Human CPA1 mutation causes digestive enzyme misfolding and chronic pancreatitis in mice, GUT 68: (2) pp. 301-312.
type of document: Journal paper/Article
number of independent citations: 31
language: English
URL 
2018

Geisz Andrea, Sahin-Toth Miklos: A preclinical model of chronic pancreatitis driven by trypsinogen autoactivation, NATURE COMMUNICATIONS 9: 5033
type of document: Journal paper/Article
number of independent citations: 25
language: English
URL 
2013

Witt H, Beer S, Rosendahl J, Chen JM, Chandak GR, Masamune A, Bence M, Szmola R, Oracz G, Macek M, Bhatia E, Steigenberger S, Lasher D, Bühler F, Delaporte C, Tebbing J, Ludwig M, Pilsak C, Saum K, Bugert P, Masson E, Paliwal S, Bhaskar S, Sobczynska-Tomaszewska A, Bak D, Balascak I, Choudhuri G, Reddy DN, Rao GV, Thomas V, Kume K, Nakano E, Kakuta Y, Shimosegawa T, Durko L, Szabó A, Schnúr A, Hegyi P, Rakonczay Z, Pfützer R, Schneider A, Groneberg DA, Braun M, Schmidt H, Witt U, Friess H, Algül H, Landt O, Schuelke M, Krüger R, Wiedenmann B, Schmidt F, Zimmer KP, Kovacs P, Stumvoll M, Blüher M, Müller T, Janecke A, Teich N, Grützmann R, Schulz HU, Mössner J, Keim V, Löhr M, Ferec C, Sahin-Tóth M: Variants in CPA1 are strongly associated with early-onset chronic pancreatitis, NATURE GENETICS 45: (10) pp. 1216-1220.
type of document:
number of independent citations: 134
language: English
URL 
2008

Rosendahl J, Witt H, Szmola R, Bhatia E, Ozsvari B, Landt O, Schulz HU, Gress TM, Pfuetzer R, Loehr M, Kovacs P, Blueher M, Stumvoll M, Choudhuri G, Hegyi P, Morsche RHT, Drenth JP, Truninger K, Macek M, Puhl G, Witt U, Schmidt H, Buening C, Ockenga J, Kage A, Groneberg DA, Nickel R, Berg T, Wiedenmann B, Boedeker H, Keim V, Moessner J, Teich N, Sahin-Toth M: Chymotrypsin c (ctrc) variants that diminish activity or secretion are associated with chronic pancreatitis, NATURE GENETICS 40: (1) pp. 78-82.
type of document:
number of independent citations: 223
language: English
URL 
Number of independent citations to these publications:527 
Scientometric data
list of publications and citations
number of scientific publications that meet accreditation criteria:
234
number of scientific publications:
234
monographs and professional books:
0
monographs/books in which chapters/sections were contributed:
2 
scientific publications published abroad that meet the accreditation criteria:
224
publications not in Hungarian, published in Hungary, meeting the accreditation criteria:
1
number of independent citations to scientific publications and creative works:
5149

 
All rights reserved © 2007, Hungarian Doctoral Council. Doctoral Council registration number at commissioner for data protection: 02003/0001. Program version: 2.2358 ( 2017. X. 31. )